Feng Tao,Du Zhijie,Yu Yuefen,et al.Research on classification of prescriptions in Treatment Record of Hundreds of Selected Ancient Prescriptions based on hierarchical clustering[J].,2021,43(01):68-71.[doi:10.3760/cma.j.cn115398-20190716-00110]
《皕一选方治验实录》方剂系统聚类分类研究
- Title:
- Research on classification of prescriptions in Treatment Record of Hundreds of Selected Ancient Prescriptions based on hierarchical clustering
- Keywords:
- Cluster analysis; Hierarchical clustering; Prescriptions; Classification; Similar prescription; Treatment Record of Hundreds of Selected Ancient Prescriptions
- 摘要:
- 目的 基于系统聚类思想，探索对方剂按照类似于类方分类的方法进行分类的实现方式。方法 选取《皕一选方治验实录》收录的581首方剂，规范药物名称，录入Microsoft Excel 2007，导入SPSS 24.0，利用系统聚类功能生成谱系图，分析581首优选古方的分类情况。结果 通过反复聚类可把581首方剂分为86类，最多的一组有29个方剂，最少的一组有2个方剂，平均每组约6.75个方剂，总体上呈现出越晚截取的组其内部方剂的相似性越低。结论 本方法可实现对方剂按照类似于类方分类的方法进行分类，可能有助于打破原有的思维束缚，进一步加深对方剂配伍规律的认识，但在分析方剂相互间的配伍规律时会减少理论线索，且未专门考虑方剂中药物的药量及性味归经问题。
- Abstract:
- Objective Based on systematic idea of clustering methods, a novel approach for classifying prescriptions was explored in the light of the method of classifying analogous prescriptions. Methods A total of 581 ancient prescriptions were selected from Treatment Record of Hundreds of Selected Ancient Prescriptions, and the standardized names of Traditional Chinese Medicines in these prescriptions were entered in Microsoft Excel 2007, then imported to SPSS 24.0 to generate dendrograms using the hierarchical clustering function. The classification of 581 selected ancient prescriptions was analyzed. Results All 581 prescriptions could be classified into 86 categories through repeated clustering, the largest group has 29 prescriptions, the smallest group has 2 prescriptions, and the average group has about 6.75 prescriptions. In general, the later the intercepted group, the lower the similarity of its internal prescriptions. Conclusion This method could realize the classification of prescriptions in the light of the method of classifying analogous prescriptions, which may help to break the original thinking bondage and further deepen the understanding of compatibility rules of prescriptions. However, its disadvantage lied in that the theoretical clues would be reduced when analyzing the compatibility rules of prescriptions and the issues of drug dosage, nature, taste and meridian categories were not specially considered.
参考文献/References:
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备注/Memo
通信作者：冯涛，Email: ffengttao@aliyun.com 基金项目：河北省中医药管理局科研计划项目(2017240)
更新日期/Last Update:
2021-01-05