《二续名医类案》中与抑郁症相关医案的用药规律探讨

Title:

Study on medication rule of depressive disorder in medical records of Er Xu Ming Yi Lei An

作者:

李涛 梅妍 张鑫 汪卫东

100053 北京，中国中医科学院广安门医院心理科

Author(s):

LI Tao;  MEI Yan;  ZHANG Xin;  WANG Wei-dong

Guanganmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China

关键词:

抑郁症; 古代医案; 用药规律; 中药频次

Keywords:

Depressive disorder; Ancient medical records; Medication rule; Application frequency of Chinese materia medica

DOI:

10.3760/cma.j.issn.1673-4246.2011.07.012

文献标志码:

A

摘要:

目的 探讨《二续名医类案》中与现代抑郁症相关医案的病因、病位、病机以及辨证规律。方法 以《名医类案》、《续名医类案》、《二续名医类案》中的医案为对象，采用Excel 建立抑郁症医案数据库，运用频数分析等方法进行总结分析抑郁症的用药规律。结果 医案中涉及的躯体症状有纳呆、倦怠、汗出、腹胀、不寐、胁痛6种，占前10名总频次的53.41%。涉及的治法以理气法最多。方剂出现频率依次是逍遥散类方＞补中益气汤＞桃仁承气汤＞加味归脾汤＞温胆汤＞六君子汤＞酸枣仁汤等。药物多数集中于柴胡＞陈皮＞白芍＞郁金＞龙骨＞当归等。结论 《二续名医类案》中抑郁症的病因、病机以及辨证用药有一定规律可循。

Abstract:

Objective To study the origin, position, pathogenesis and differentiation rule of depressive disorder in ancient medical records, Er Xu Ming Yi Lei An. Methods Study medical records in ancient medical books, Ming Yi Lei An, Xu Ming Yi Lei An, Er Xu Ming Yi Lei An. Adopt Excel to establish medical records’ database about depressive disorder, and use frequency analysis method to summarize medication rule of Chinese materia medica for treating depressive disorder. Results Six body symptoms referred in medical records are anorexia, lassitude, sweating, abdominal distension, insomnia, and hypochondriac pain, account 53.41% in top ten symptoms; regulating Qi method is the most frequently used treatment; The most frequently use prescriptions in a descending order are Xiaoyaosan, Buzhong Yiqi Tang, Taoren Chengqi Tang, Modified Guipi Tang, Wendan Tang, Liujun Zi Tang, Suanzaoren Tang, et. Most frequently applied medical herbs in a descending order are bupleurum, dried tangerine peel, white peony alba, tumeric root tuber, fossilia ossis mastoid, and Chinese angelica, et. Conclusion There are certain rules in the origin, pathogenesis, diagnosis and prescriptions of depressive disorder in ancient medical records, Er Xu Ming Yi Lei An.